This research work is focused on development and characterization of the easily manufacturing nanostructured systems for enhanced delivery of cytostatic agents based on irinotecan and curcumin. Developed nano-systems only consist of active therapeutic substances and possess good physiochemical stability and redispersibility of its lyophilisates. Both in vitro and in vivo tests showed improved effectivity of the prepared nanoformulations in comparison with pure cytostatic analogues with simultaneous significant suppressing of the side effects that is promising for further clinical trials.
| ISBN: | 978-80-7454-970-0 |
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| EAN: | 9788074549700 |
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| Počet stran |
50 stran |
| Datum vydání |
08. 12. 2020 |
| Pořadí vydání |
První |
| Jazyk |
anglický |
| Vazba |
e-kniha - pdf |
| Autor: |
Haijun Xiao |
| Nakladatelství |
Univerzita Tomáše Bati ve Zlíně |
| Tématická skupina |
999 - nezařazeno |
| Neprodejná publikace. Publikaci je možné poptávat zde: Volně dostupné na http://hdl.handle.net/10563/45956 |
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